According to Greek mythology, Nessus was a centaur, the son of Ixion and Nefele, the Cloud. Once, Nesso tried to rape Dejanira, the wife of Heracles, to get revenge on the hero for having once offended her.
Heracles shot Nesso dead with arrows. Before he died, the centaur maliciously told Dejanira that his blood would be able to make Heracles love her forever.
When Heracles' interest in his wife waned, Dejanira, unaware that Nesso's blood was actually a powerful poison, applied it to a tunic of her husband. When Heracles put the tunic on, he immediately felt the effect of the poison, burning his flesh, and eventually died.